Large-scale validated antibodies for immunohistochemistry
Many antibody suppliers provide very little information and images of how an antibody stains. References are often limited to a positive and negative control on their website. When pathologists and researchers use these antibodies, they don’t know the full staining behavior of an antibody because they often don’t have the time or access to enough different tissues to perform in-house validation of the antibody. This can cause serious problems because researchers cannot know if they can trust the antibody and the data they have generated in their studies.
MS Validated Antibodies (MSVA) is dedicated to providing optimal monoclonal antibodies for immunohistochemistry and to providing users with unique product documentation that allows them to know as much as possible about their antibodies. Key features of the MSVA package include:
Extensively validated, high-quality antibodies are key to successful experiments. Optimal antibodies are especially critical for multiplex fluorescence immunohistochemistry where even a single cross-reactive antibody can ruin an entire experiment.
The majority are rabbit recombinant antibodies. These have the advantage of being fully reproducible, as they are not produced by potentially unstable hybridoma cells, but “in the lab” based on the known DNA sequence of the antibody chains.
For a quote request or product information, please contact us using quotes@bio-connect.nl.
Gorbokon, N et al. Prevalence of S-methyl-5′-thioadenosine Phosphorylase (MTAP) Deficiency in Human Cancer: A Tissue Microarray Study on 13,067 Tumors From 149 Different Tumor Types. Product: Recombinant rabbit monoclonal antibody, clone MSVA-741R.
Uhlig, R. et al. Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas. Product: Primary antibody specific for CPA1 (mouse monoclonal, MSVA-601M)
Dum, D et al. Semi-automated validation and quantification of CTLA-4 in 90 different tumor entities using multiple antibodies and artificial intelligence. Product: Primary antibody specific for CTLA-4. Rabbit recombinant, clone MSVA-152R, Cat#: 3451–152 R.
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