Custom VLP Membrane Protein Expression Service

Membrane proteins play an important role in life activities. As important drug targets, membrane proteins are limited in application due to their low yield, difficult preparation, and poor stability. Sino Biological has built a VLP (virus-like particle) technology platform based on the HEK293 expression system, which can present the target membrane protein on the surface of VLP, making the detection much easier.

Currently, they have developed a full range of membrane proteins with good activity including GPRC5D, CLDN18.2, CLDN6 as catalog products. Sino Biological also provide customized services to expedite drug research and development process.

Service details

Case study

Immobilized Human GPRC5D-VLP (Full Length) Protein (Cat: 24447-HNAH) at 5 μg/mL (100 μL/well) can bind anti-GPRC5D Antibody, the EC50 is 3-10 ng/mL.

Immobilized Human Claudin 18.2-VLP (Full Length) Protein (Cat: 30025-HNAH) at 5 μg/mL (100 μL/well) can bind Anti-Human claudin18.2 Antibody, Human IgG1, the EC50 is 5-20 ng/mL.

Immobilized Human Claudin 6-VLP (Full Length) Protein (Cat: 16658-HNAH) at 5 μg/mL (100 μL/well) can bind Anti-Human CLDN6 Antibody, Human IgG1, the EC50 is 2-10 ng/mL.

Good freeze-thaw stability

Good batch consistency

Bio-Connect Life Sciences supplies Sino Biological products and services in the Benelux. If you have any questions, please contact the helpdesk.