As 3D hollow fiber perfusion bioreactors are increasingly recognized as superior to and more in vivo like than traditional 2D flask culture methods, we are proud to champion a new era in cell culture technology.
3D high-density culture in a hollow fiber bioreactor not only supports these principles, but also takes them a step further by allowing the cells themselves to create their own specific microenvironment. This promotes proper cell physiology and creates an environment that mimics of in vivo conditions. As a result, it facilitates complete and uniform post-translational modifications while preserving bioactivity and cell physiology. The auto-support provided by cell-secreted cytokines is what enables FiberCell’s CDM HD, a chemically defined medium for high-density culture, to achieve near-universal efficacy with a simplified formulation.
Technical advantages of FiberCell Systems
LESS DISRUPTION, LESS WORK & LESS WASTE Maintenance is only 15 minutes a day. Passage numbers are irrelevant when you can achieve continuous cell culture production for many months, as splitting of cells is not required.
CLEAN, CONCENTRATED & SIMPLIFIED HARVEST HFBRs allow 10-100X higher concentration of secreted products, and reduced apoptosis and shear on cells. This results in significantly lower host cell protein and DNA contamination, along with reduced membrane fragments.
UNIQUE 3-D POROUS SUPPORT Enables in vivo like conditions for optimal, high-density cell cultivation and cell co-cultivation. Fiber geometry mimics the mammalian capillary bed.
FiberCell’s system can be used for a wide variety of applications
Discover the real power of Hollow Fiber Cell Culture. Learn more about their full range of applications.
Please also take a look into FiberCell’s brand new Cell Culture Manual which is packed with updated protocols for hybridoma culture, recombinant protein production, cell co-cultivation, mesenchymal stem cell culture, and exosome production. Dive into decades of expertise distilled into one comprehensive guide.
Direct contact technical support
Find products for your research
