31 March 2025

ESR1 Control Kit Featuring Comprehensive 16 Mutation Coverage

Revolutionizing the detection of ESR1 mutations, the ZeptoMetrix ESR1 Control Kit ensures precise and reliable results, setting a new standard in laboratory diagnostics.


ZeptoMetrix, an Antylia Scientific company, is pleased to announce the launch of its new ESR1 Control Kit. This groundbreaking product is specifically designed to enhance the accuracy and reliability of ESR1 mutation detection, which is crucial for guiding effective breast cancer therapy.

The Critical Role of ESR1 Mutations for Breast Cancer Therapy

ESR1 mutations have been recognized as a significant factor in the development of resistance to endocrine therapies in breast cancer treatment. These mutations can emerge over the course of therapy, making ongoing monitoring and precise detection critical for adjusting treatment plans and improving patient outcomes.

Recent studies have underscored the critical nature of ESR1 mutations in the context of metastatic breast cancer. Research has demonstrated that these mutations affecting the function of the estrogen receptor can emerge during the course of therapy, driving the need for ongoing monitoring and accurate detection to adjust treatment plans effectively.

ESR1 Control Kit – a crucial tool

With ZeptoMetrix ESR1 Control Kit, laboratories can now refine their detection methods and contribute to more informed clinical decisions.

Key Features

  • Only Kit on the Market with 16 Mutations: The ZeptoMetrix ESR1 Control Kit stands out as the only product available that includes 16 clinically relevant ESR1 mutations. This exclusive feature provides laboratories with unmatched capabilities in mutation detection and quality control.
  • External Quality Control: The kit serves as an external quality control for ESR1 mutation assays, providing a standard against which test results can be measured.
  • Comprehensive Mutation Coverage: With four vials containing 4 ESR1 mutations each and a wild-type cfgDNA control, the kit offers broad coverage for clinically relevant ESR1 mutations – see full list below.
  • Four Vials per Kit: Each kit includes four vials, allowing for multiple runs and ensuring consistency in test performance.
  • 1% Variant Allele Frequency (VAF): The 1% VAF provides a challenging yet achievable target for mutation detection, pushing the sensitivity limits of current assay technologies.

ZeptoMetrix is committed to providing innovated quality control products that empower laboratories as they strive to deliver accurate diagnostic results. The new ESR1 Control Kit exemplifies this commitment, offering unparalleled mutation coverage to support the vital work of clinicians and researchers in the fight against breast cancer.

Mutations covered by ESR1 Control Kit by ZeptoMetrix

ESR1 Control Kit Featuring Comprehensive 16 Mutation Coverage

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