13 March 2025

Endotoxin-Free Products: Made in the US

Sino Biological‘s Center for Bioprocessing (C4B) in Texas produces endotoxin-free proteins with levels below the quantification limit (BQL).

Endotoxin-free proteins are crucial for ensuring accurate and reliable scientific research and drug development in endotoxin-sensitive applications. Sino Biological’s new C4B center in Texas exceeds industry standards (0.5 EU/mg as per USP <85>), making it ideal for preclinical animal studies, precise detection, and cell-based assays.

Sino Biological’s Endotoxin-Free Guarantee

Endotoxin-free plasmids and specialized mammalian expression systems
Endotoxin-free buffer with filtration
Low endotoxin-affinity plastic containers
Regular Clean-in-place (CIP)

Featured Endotoxin-free Proteins
Endotoxin-Free	High purity > 90% by SEC-HPLC
Ideal for pre-clinical studies	Ready to use for animal injections

Molecule	Cat#	Purity	Endotoxin	Tag
B7-H3	29849-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
B7-H3	11188-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
TROP-2	10428-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
CEACAM-5/CD66e	11077-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
PD-L1/B7-H1	10084-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
CD40/TNFRSF5	10774-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
EGFR	10001-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
CD25/IL-2R alpha	10165-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
Siglec-3/CD33	12238-H08H-UE	≥90% (SEC-HPLC)	BQL	C-His
4-1BB/CD137	10041-H38H-UE	≥90% (SEC-HPLC)	BQL	C-mlgG2a
LAG-3	16498-H38H-UE	≥90% (SEC-HPLC)	BQL	C-mlgG2a
CD19	11880-H38H-UE	≥90% (SEC-HPLC)	BQL	C-mlgG2a

You can request a quote for the Endotoxin-free Proteins here, or contact your account manager for more information.

Contact Account Manager

Why choose C4B for endotoxin-free protein production?

One-stop protein CRO service Optimized expression platforms ensure the highest chances of success	Fast turnaround time Customized antibodies & proteins delivered in as fast as 2 weeks
Superior quality >90% purity by SEC-HPLC, endotoxin-free level	Advanced equipment State-of-the-art equipment & minimal endotoxin during processing
Scalable production 24 well plates to 25 L bioreactors, we cover all your protein needs from screening to production scale	Optimized mammalian platforms mammalian expression system to ensure minimal endotoxin levels

Sino Biological’s Center for Bioprocessing (C4B) in Texas is developing more endotoxin-free proteins. Our specialized mammalian expression systems and rigorous quality control ensure minimal endotoxin levels, making these products ideal for pre-clinical studies. You can contact us to inquire about the progress of the development. In addition, we also support custom development services!