Bio X Cell’s Isotype Controls with Functional Antibodies
Combine Bio X Cell‘s isotype controls with functional grade antibodies to enhance research accuracy by eliminating non-specific binding and ensuring precise, reliable experimental results.
This is the perfect opportunity to enhance your research while ensuring the highest level of experimental accuracy. Save now 20% on isotype controls when purchased with a functional grade antibody of equal or greater value.
How to Redeem Your Discount
Request Your Personal Discount Code via this link.
Apply the code when purchasing a functional grade antibody and an isotype control.
Once you’ve requested and received your unique promo code, enter the promo code in the comment section of your webshop order or include it in your email order. The promotion cannot be applied retroactively.
Important: For webshop orders, enter the promo code in the comment section. Do not use the coupon code field, as it will cause an error.
Standard shipping costs still apply.
Bio-Connect reserves the right to modify, cancel, or withdraw this promotion at any time.
Isotype controls are essential for validating antibody-specific effects in blocking, neutralization, depletion, and activation experiments. Bio X Cell’s in vivo-ready isotype controls are:
Ultra-pure – Free from preservatives and stabilizers
Ultra-low endotoxin – Ensuring minimal interference in experiments
Optimized for in vivo use – Designed for reliable and reproducible results
Example Pairing for Your Research
Functional Antibody:InVivoPlus Functional PD-1 (CD279) – A widely used immune checkpoint inhibitor for immunology, cancer biology, and neuroscience research.
When conducting in vivo and in vitro experiments, ensuring the accuracy and reliability of your results is crucial. One of the best ways to achieve this is by using isotype control antibodies alongside functional grade antibodies. Bio X Cell provides high-quality isotype controls specifically designed to complement their functional grade antibodies, helping researchers eliminate background noise and validate their findings.
Key Benefits of Using Bio X Cell’s Isotype Controls:
Eliminating Non-Specific Binding: Ensures that any observed biological effects are due to antigen-specific interactions rather than unintended Fc receptor binding.
Enhancing Data Reliability: Helps differentiate between specific and non-specific signals, leading to more accurate conclusions.
Optimized for In Vivo Use: Bio X Cell’s isotype controls are ultra-pure, preservative-free, and have ultra-low endotoxin levels, making them ideal for in vivo studies.
How Functional Grade Antibodies Work
Functional grade antibodies are designed for applications such as blocking, neutralization, depletion, and activation in both in vitro and in vivo settings. Bio X Cell’s functional grade antibodies are free from preservatives and stabilizers, ensuring minimal interference in biological assays.
When used together with isotype controls, functional grade antibodies provide:
Accurate Functional Assays: By controlling for non-specific effects, researchers can confidently assess the biological function of their target antibody.
Reliable In Vivo Studies: Ensures that immune responses observed in animal models are due to the intended antibody function rather than background interference.
Consistent Experimental Outcomes: Reduces variability and enhances reproducibility across experiments.
Best Practices for Using Isotype Controls with Functional Grade Antibodies
To maximize the effectiveness of Bio X Cell’s isotype controls and functional grade antibodies:
Match the Isotype Control Precisely: Ensure that the isotype control matches the species, isotype, and subclass of the functional antibody.
Use Identical Experimental Conditions: Treat isotype control groups the same as functional antibody-treated groups to accurately assess non-specific effects.
Optimize Concentrations: Use the same concentration of isotype control and functional antibody to ensure valid comparisons.
Incorporate Proper Controls: Combine isotype controls with other experimental controls to strengthen data interpretation.
Ensure Accurate Results with Bio X Cell’s Isotype Control Antibodies
Isotype control antibodies serve as negative controls, allowing researchers to differentiate between non-specific background signals and the specific effects of their primary antibody. To be effective, they must match the species and isotype of the primary antibody but lack specificity for the target species.
Key Features of Bio X Cell’s Isotype Controls:
✔ >95% purity confirmed via SDS-PAGE ✔ Available in InVivoMab™ and InVivoPlus™ formats ✔ Ready for in vivo administration ✔ Azide and carrier protein-free for minimal interference ✔ Available in large quantities (mg to g scale) ✔ High concentrations (3-10 mg/ml)
Using Bio X Cell’s isotype controls in combination with their functional grade antibodies is essential for generating reliable, reproducible, and biologically relevant data. By minimizing background noise and ensuring specific antibody interactions, researchers can confidently advance their studies in immunology, oncology, and beyond.
Contact your account manager for more information on Bio X Cell’s isotype controls and functional grade antibodies.
Bio X Cell’s Isotype Controls with Functional Antibodies
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