RabMabs on cancer cell proliferation

The fundamental abnormality resulting in the development of cancer is the continual unregulated proliferation of cancer cells. Rather than responding appropriately to the signals that control normal cell behavior, cancer cells grow and divide in an uncontrolled manner, invading normal tissues and organs and eventually spreading throughout the body. Ectopic receptors or kinases (e.g. Bcr-Abl, EGFR, HER2, c-Met, and Raf), constitutive activation of many signal transduction pathways (such as PI3K/Akt pathway, MAPK pathway, Wnt pathway, Hippo pathway) and transcription regulators (such as c-myc, Smads, STATs, YAP) are commonly known to be involved in cancer cell proliferation.

Selected antibodies for cancer proliferation research

Rabbit monoclonal antibodies from ABclonal.

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